Insight into plant annexin function

Insight into SUCNR1 (GPR91) structure and function.

SUCNR1 (or GPR91) belongs to the family of G protein-coupled receptors (GPCR), which represents the largest group of membrane proteins in human genome. The majority of marketed drugs targets GPCRs, directly or indirectly. SUCNR1 has been classified as an orphan receptor until a landmark study paired it with succinate, a citric acid cycle intermediate. According to the current paradigm, succinat...

Mitophagy: New Insight into the Cardiovascular Aging  

Plant-Pathogen Interactions: A Brief Insight into a Complicated Story

Pseudomonas syringae is a bacterial plant pathogen that can lead to heavy losses in crop production. Th is bacteria is a very good model to study the infection processes, as it can cause disease in Arabidopsis thaliana, a well-studied plant model. Th is text presents an overview of the bacterial pathogenesis from a molecular biology perspective, and explains the role of plant responses in stopp...

Insight into Biochemical Characterization of Plant Sesquiterpene Synthases

A fast and reproducible protocol was established for enzymatic characterization of plant sesquiterpene synthases that can incorporate radioactivity in their products. The method utilizes the 96-well format in conjunction with cluster tubes and enables processing of >200 samples a day. Along with reduced reagent usage, it allows further reduction in the use of radioactive isotopes and flammable ...

Proteomic Insight into the Molecular Function of the Vitreous

The human vitreous contains primarily water, but also contains proteins which have yet to be fully characterized. To gain insight into the four vitreous substructures and their potential functions, we isolated and analyzed the vitreous protein profiles of three non-diseased human eyes. The four analyzed substructures were the anterior hyaloid, the vitreous cortex, the vitreous core, and the vit...